Age of Collagen in Intracranial Saccular Aneurysms
نویسندگان
چکیده
منابع مشابه
Age of collagen in intracranial saccular aneurysms.
BACKGROUND AND PURPOSE The chronological development and natural history of cerebral aneurysms (CAs) remain incompletely understood. We used (14)C birth dating of a main constituent of CAs, that is, collagen type I, as an indicator for biosynthesis and turnover of collagen in CAs in relation to human cerebral arteries to investigate this further. METHODS Forty-six ruptured and unruptured CA s...
متن کاملType III Collagen Deficiency in Saccular Intracranial Aneurysms
Background and Purpose—We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a red...
متن کاملType III collagen deficiency in saccular intracranial aneurysms. Defect in gene regulation?
BACKGROUND AND PURPOSE We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a red...
متن کاملSaccular intracranial aneurysms in autosomal dominant polycystic kidney disease.
The literature on the association of intracranial aneurysms in autosomal dominant polycystic kidney disease (ADPKD) consists mainly of case reports and small series of patients. To provide a more-detailed description of this association and its frequency, the records of all ADPKD patients with saccular intracranial aneurysms, all ADPKD autopsy cases including brain examination, and sex- and age...
متن کاملSystemic connective tissue abnormalities in patients with saccular intracranial aneurysms.
OBJECTIVES Our purpose was to identify the incidence and significance of markers of systemic connective tissue abnormalities (CTA) in patients with saccular intracranial aneurysms (SIA). MATERIALS AND METHODS This prospective case-control study included 199 consecutive patients with SIA (103 women and 96 men, mean age - 43.2 years) and 194 control patients - blood donors (108 - men, 86 - wome...
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ژورنال
عنوان ژورنال: Stroke
سال: 2014
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.114.005461